Craniofacial mouse models
Privacy: The repository will never disclose which, if any, independent investigator is conducting research on a mutant strain. Photographs of mutants will remain public indefinitely. In addition, Repository staff may conduct further research themselves on these strains. New data will be posted as it becomes available.
For more detail, please click on the mutation symbol or gene name.
Mutants are maintained either as live colonies or cryopreserved germplasm. When an investigator expresses interest in a particular live strain, 2 breeder pairs will be provided as soon as possible for the price of shipping. Cryopreserved strains are available for a fee from the JAX Cryopreservation Service.
Interested parties may contact faces@jax.org.
Mapped Models
| Mutation Symbol | Mutation Name | Gene Symbol | Phenotype | Chr. | Availability |
| Arsb<m1J> | mutation 1 Jackson | Arsb | craniofacial, skeletal, neurological, hearing | 13 | Cryo only |
| cfe-se6J | cauliflower ear-short ear 6J | Bmp5 | Short ear pinnae | 9 | Cryo only |
| cfe-se7J | cauliflower ear-short ear 7J | Bmp5 | Short nose, short ear pinnae | 9 | Cryo only |
| cfe-se8J | cauliflower ear-short ear 8J | Bmp5 | Short ear pinnae | 9 | Cryo only |
| dhe | disheveled hair and ears | Lmna | small ears, sparse coat; model of human laminopathies | 3 | Live Colony |
| din | dense incisors | din | Incisors do not fully erupt | 16 | Cryo only |
| Eask | ear askew | misplaced and malformed pinna | 8 | Live colony | |
| frg | froggy | frg |
craniofacial, skeletal, size, deafness, eye, movement anomalies, homozygous lethality (See Photo) |
13 | Cryo only |
| He | helicopter ears | He |
ear pinna angled outward (See Photo) |
4 | Cryo only |
| Hyp-2J | hypophosphatemia 2 Jackson | Phex | small cranium, abnormal postnatal growth | X | Cryo only |
| Hyp-Duk | hypophosphatemia, Duke | Phex | craniofacial, abnormal postnatal growth | X | Cryo only |
| hyrh | hydrocephalaus with rhinitis | Hydin | craniofacial | 8 | Live colony |
| lear | little ears | Prkra |
Smaller ear pinna and smaller overall body size |
2 | Live colony |
| Lrp4<mdig> | missing digits 2 Jackson | Lrp4 | skeleton, digits | 2 | Cryo only |
| ne | no eyelid | ne | eyes, skeleton, and coat color (See Photo) | 3 | Live colony |
| nee | nose eyes ear | Sh3pxd2b | abnormal postnatal growth; decreased size; short snout and domed cranium | 11 | Cryo only |
| sbse | small body and short ears | sbse |
small body and short ears (See Photo) |
4 | Live colony |
| sedc | spondyloepiphyseal dysplasia congenita | Col2a1 | abnormal postnatal growth; impaired hearing; disorganized retinal layers; head bobbing | 15 | Cryo only |
| shk | sharkey | Sostdc1 |
teeth, hearing (See Photo) |
12 | Live colony |
| snol | snubnose-like | snol | Short nose, odd face and body shape, and kinked tail (See Photo) | 4 | Live colony |
| Sofa | short face | Pfas |
Short nose, domed head, wide set eyes (See Photo) |
11 | Cryo only |
| stn | stunted | stn |
short face (See Photo) |
19 | Cryo only |
| whe | white eyes | whe | Domed skull and small, white vascular area on the cornea which is also attached to the iris in one or both eyes | 11 | Cryo only |
Unmapped models
*Select "more details" for photo and additional information| Strain Name | Phenotype | Availability | |
| C57BL/6J-Tg(NSElgmb2)-nm3799 | short nose | cryo only | more details |
|
B6.129P2-Apoa1tm1Unc/J-nm2834 |
short nose | cryo only | more details |
|
B6AF1/J-nm3014 |
short nose |
cryo only | |
|
C57BL/6J-nm3140 |
short front legs, small ear pinnae, and a square, fat body |
cryo only | |
|
B6CBA-Tg(HDexon1)62oGpb/J-nm3250 |
small overall body size and a short, rounded nose |
cryo only | |
|
NOD.ALR-(D17Mit16-D17Mit10 )/LtJ-nm3283 |
short nose |
cryo only |
Last Modified: March 26, 2012
